364 Huron Street, Toronto was constructed in 1879 and first occupied in 1880. Its first occupant was Charles Williams - a local bricklayer - who lived here between 1880 and 1881. 

364 Huron Street was originally semi-detached. As noted above, 364 Huron Street was originally home to Charles Williams - a local bricklayer. 366 Huron Street - its counterpart - was originally home to Richard H. Harman - a local bricklayer and builder. Harman resided at 366 Huron Street from its construction through the 1890s. The original 19th century building at 366 Huron Street has since been demolished and replaced with a modern building. 

Constructed in 1879, 364 Huron Street is one of the oldest extant properties in Huron-Sussex. 

City of Toronto Directories note that 364 Huron Street was 1 of the first 12 houses built on Huron Street north of College Street. This was during a neighbourhood building boom in 1879. Prior to 1879, no houses had been constructed on Huron Street north of College Street. 

City of Toronto Directories note that since 1885, 364 Huron Street has been associated with small scale commercial and retail use. Its first commercial use (circa. 1886) was as the business and home of Paul F. Swiderski - a local grocer - during the 1880s. 364 Huron Street remained in use as a grocers for several decades. By 1890, the grocer was Frances Boake and by the 1910s, the grocer was Joseph Weston.

364 Huron Street is of the Ontario Gothic Revival Cottage (Ontario House) style. 364 Huron Street is 1 of only 4 Ontario Gothic Revival Cottages (Ontario Houses) in the Huron-Sussex neighbourhood. 3 of these 4 cottages (including 364 Huron Street) are slated for demolition in the near future.