Property was formerly known as 189-191 College Street. 

The property was constructed c.1886-1887 as as semi-detached residential building, first occupied by Mary Mitchell and her husband J.E. Mitchell, of Mitchell, Miller and Co. (a storage company), and Edward Moore, who was a money broker.

Occupants of this property did not remain longer than five years, and The Toronto School of Languages as the first long-term tenant (1915-1925), and the property was converted into commercial use for the very first time, and reverted to residential after the Toronto School of Languages.

The Royal Canadian Institute, Canada’s oldest scientific society that was formed in 1849, Toronto and known today as RCIScience, relocated to 191 college occupied the building for over thirty years beginning 1952, until 1986. The reason for the relocation was because their original location (198 College st), on the University of Toronto campus was to be demolished due to the construction of the Walberg Memorial Building in the late 1940s.

It has been home to Prenub Pub since 2014. 

A 31-storey mixed-use rental building (490 units) entirely out of mas timber designed by Icon Architects for Unix Housing Group is proposed for this site. 

Additionally, the properties at 191 College Street have design value as surviving examples of late 19th century house form buildings on College Street, west of McCaul Street, with detailing from the popular architectural styles of the Victorian era, including the Italianate and Gothic Revival. Anchoring the east end of a trio of semi-detached house form buildings that were constructed together, the pair is further distinguished by the surviving decorative wood detailing in the gables.
Contextually, the properties at 191 College Street (including the property with the convenience address of 189 College Street) are valued for their role in defining, supporting and maintaining the historical character of College Street, west of McCaul Street, which originally developed as a residential neighbourhood. With their later conversion for mixed commercial and residential uses, the buildings reflect the ongoing evolution of the thoroughfare
The buildings at 191 College Street are historically, visually and physically linked to their setting in the block on the south side of the street where they are part of a series of complementary late 19th century house form buildings adjoining both sides of the intersection with Henry Street.